The naphthoylindole series tends to

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{"type":"standard","title":"Pavani Reddy","displaytitle":"Pavani Reddy","namespace":{"id":0,"text":""},"wikibase_item":"Q99520827","titles":{"canonical":"Pavani_Reddy","normalized":"Pavani Reddy","display":"Pavani Reddy"},"pageid":65375773,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Pavani_Reddy.jpg/330px-Pavani_Reddy.jpg","width":320,"height":359},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/a/ac/Pavani_Reddy.jpg","width":478,"height":536},"lang":"en","dir":"ltr","revision":"1289543319","tid":"07ca1943-2cb1-11f0-b6c2-3ce9c19ff287","timestamp":"2025-05-09T08:38:50Z","description":"Indian model and actress","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Pavani_Reddy","revisions":"https://en.wikipedia.org/wiki/Pavani_Reddy?action=history","edit":"https://en.wikipedia.org/wiki/Pavani_Reddy?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Pavani_Reddy"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Pavani_Reddy","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Pavani_Reddy","edit":"https://en.m.wikipedia.org/wiki/Pavani_Reddy?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Pavani_Reddy"}},"extract":"Pavni Reddy also known as Pavani is an Indian actress who predominantly appears in Tamil and Telugu language films. She acted in a supporting role in the Tamil film Thunivu (2023). In 2021, she was a contestant on the reality series Bigg Boss 5 and finished as the 2nd runner up. She is also known for playing the lead in the Tamil-language television series Chinna Thambi.","extract_html":"

Pavni Reddy also known as Pavani is an Indian actress who predominantly appears in Tamil and Telugu language films. She acted in a supporting role in the Tamil film Thunivu (2023). In 2021, she was a contestant on the reality series Bigg Boss 5 and finished as the 2nd runner up. She is also known for playing the lead in the Tamil-language television series Chinna Thambi.

"}

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{"slip": { "id": 3, "advice": "Don't eat non-snow-coloured snow."}}

{"type":"standard","title":"JWH-098","displaytitle":"JWH-098","namespace":{"id":0,"text":""},"wikibase_item":"Q6109184","titles":{"canonical":"JWH-098","normalized":"JWH-098","display":"JWH-098"},"pageid":28757735,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/JWH-098.svg/330px-JWH-098.svg.png","width":320,"height":391},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/JWH-098.svg/512px-JWH-098.svg.png","width":512,"height":626},"lang":"en","dir":"ltr","revision":"1274426831","tid":"efb6f2c8-e527-11ef-af79-b29fff234172","timestamp":"2025-02-07T07:48:36Z","description":"Chemical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/JWH-098","revisions":"https://en.wikipedia.org/wiki/JWH-098?action=history","edit":"https://en.wikipedia.org/wiki/JWH-098?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:JWH-098"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/JWH-098","revisions":"https://en.m.wikipedia.org/wiki/Special:History/JWH-098","edit":"https://en.m.wikipedia.org/wiki/JWH-098?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:JWH-098"}},"extract":"JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081, but has markedly different affinity for the CB1 and CB2 receptors. While JWH-081 is around tenfold selective for CB1 over CB2, in JWH-098 this is reversed, and it is around four times weaker than JWH-081 at CB1 while being six times more potent at CB2, giving it a slight selectivity for CB2 overall. This makes JWH-098 a good example of how methylation of the indole 2-position in the naphthoylindole series tends to increase CB2 affinity, but often at the expense of CB1 binding.","extract_html":"

JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081, but has markedly different affinity for the CB1 and CB2 receptors. While JWH-081 is around tenfold selective for CB1 over CB2, in JWH-098 this is reversed, and it is around four times weaker than JWH-081 at CB1 while being six times more potent at CB2, giving it a slight selectivity for CB2 overall. This makes JWH-098 a good example of how methylation of the indole 2-position in the naphthoylindole series tends to increase CB2 affinity, but often at the expense of CB1 binding.

"}

{"type":"standard","title":"Kullorsuaq Island","displaytitle":"Kullorsuaq Island","namespace":{"id":0,"text":""},"wikibase_item":"Q6443141","titles":{"canonical":"Kullorsuaq_Island","normalized":"Kullorsuaq Island","display":"Kullorsuaq Island"},"pageid":28642735,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Kullorsuaq-Island.jpg/330px-Kullorsuaq-Island.jpg","width":320,"height":180},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/e/e5/Kullorsuaq-Island.jpg","width":3872,"height":2176},"lang":"en","dir":"ltr","revision":"1229095755","tid":"eefcacec-2a8f-11ef-b296-1b82d23c7979","timestamp":"2024-06-14T20:51:55Z","description":"Island in Greenland","description_source":"local","coordinates":{"lat":74.6,"lon":-57.13333333},"content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Kullorsuaq_Island","revisions":"https://en.wikipedia.org/wiki/Kullorsuaq_Island?action=history","edit":"https://en.wikipedia.org/wiki/Kullorsuaq_Island?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Kullorsuaq_Island"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Kullorsuaq_Island","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Kullorsuaq_Island","edit":"https://en.m.wikipedia.org/wiki/Kullorsuaq_Island?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Kullorsuaq_Island"}},"extract":"Kullorsuaq Island is an island in the Avannaata municipality in northwestern Greenland. The name of the island means \"a big thumb\" in the Greenlandic language.","extract_html":"

Kullorsuaq Island is an island in the Avannaata municipality in northwestern Greenland. The name of the island means \"a big thumb\" in the Greenlandic language.

"}